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3 In normoxia, HIF1A protein is targeted for degradation by cytosolic prolyl hydroxylases, while in hypoxia, these prolyl hydroxylases are inhibited, allowing HIF1A to translocate to the nucleus, dimerize with HIF1 protein, and the dimer then binds to hypoxia response elements to modulate transcription of target genes, prompting changes in metabolism and angiogenesis to promote survival

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[31] To commemorate the 20th anniversary of 9/11, the Sanitation Foundation launched an online exhibition detailing "the incredible and largely unknown story of the vital role that the New York City Department of Sanitation (DSNY) played in the rescue and recovery efforts following the terrorist attacks of September 11, 2001"

Theyre also helpful for people who dont get enough B12 from their diet (spoiler: often vegetarians and vegans) and for people whose guts cant break down and absorb the vitamin

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