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Acetyl-CoA additionally acts as the carbon donor for manufacturing lipid chains rich in double bondsPUFAs (Li et al., 2021b)

DHODH and GPX4 systems are complementary, and when the function of one system decreases, the other system increases, maintaining antioxidant capacity [99, 100]

Additionally, lipids such as prostaglandins can modulate immune responses and promote angiogenesis, further supporting tumor growth and metastasis (145)

213 The key molecular mechanism is the suppression of NF-B pathway activated by cytokines such as TNF- and IL-1

Peripheral neuropathy (PN) In PN, nerves in the arms and legs are damaged, leading to a variety of symptoms, including pain, burning, numbness, tingling, loss of balance and co-ordination, and muscle weakness