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In hemodialysis patients, due to reduced renal clearance, carnitine depletion and acylcarnitine accumulation become significant, resulting in an abnormal increase in the ratio of acylcarnitine to free carnitine in plasma, which in turn inhibits cardiac fatty acid metabolism [261]

Remdesivir for treatment of COVID-19: combination of pulmonary and IV administration may offer aditional benefit

Glutathione is generally a safe ingredient for use as a dietary supplement

Smart stimuliresponsive nanoparticles are engineered to release drugs triggered by physiological stimuli (e.g., low pH, hypoxia, high ROS, GSH, inflammation, and enzymes) within specific disease microenvironments, or exogenous energetic stimuli (e.g., temperature, light, ultrasound, and magnetic field)

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