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Therapeutic strategies developed and tested in the past Significant progress has been made by the neurofibromatosis research community, including the genetic cause of NF1, the cellular function of the neurofibromin protein, and the identification of cellular components that contribute to the tumours developed in NF1

Grnborg M, Kristiansen TZ, Stensballe A, Andersen JS, Ohara O, Mann M, et al

Inhibition of the neuronal NFB pathway attenuates bortezomib-induced neuropathy in a mouse model

The RNA samples were then shipped to an NGS facility (Admera Health, NJ, USA) for sequencing

Sui M, Jiang X, Chen J, Yang H, Zhu Y