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Conclusion: S100B and S100B-creatinine ratio did not show significantly higher values after ischemic strokes and was not feasible to differ ischemic stroke patients from healthy controls Disclosure of interest: KK: nothing to disclose, CF: nothing to disclose, FB: nothing to disclose, GH: nothing to disclose E-Posters - NOVEL TARGET/ EXPERIMENTAL FIDINGS TO CLINICAL TRANSLATION 06.00 - NOVEL TARGET/ EXPERIMENTAL FIDINGS TO CLINICAL TRANSLATION - 06.01 - PATHOPHYSIOLOGY OF STROKE / TRANSLATIONAL MEDICINE P2575 - ESOC25-571 ASTROCYTE NEUREXIN1 IS A POTENTIAL TARGET FOR NEUROPROTECTION IN ACUTE ISCHEMIC STROKE Baoshan Qiu 1 , Yilong Wang 1 1 Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China Background and Aims: Persistent brain injury following acute ischemic stroke significantly affects prognosis, but its mechanisms remain poorly understood

Carroll, S