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Se realiz un anlisis de corte transversal de dos grandes estudios prospectivos realizados en China el Shanghai Womens Health Study y el Shanghai Mens Health Study que incluyeron a 56,195 personas (edades, 40-75 aos), para evaluar la asociacin entre la ingesta diettica de colina y el diagnstico autoinformado de enfermedad del hgado graso (53)

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Thus, substantial and mounting evidence supports a direct contributory role of gut microbiota as a participant in CVD pathogenesis, and preclinical studies indicate that the therapeutic targeting of microbial contributors to the TMAO metaorganismal pathway may hold promise as a novel approach for the prevention or treatment of CVD

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