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Inhibition of MAT2A by shRNA or inhibitors has reduces the proliferation of several cancer cell lines through inducing the global depletion of H3K36me3, and MAT2A knockdown prolonged the median survival in DIPG13p model mice (137)

[DOI] [PubMed] [Google Scholar] 75.Suzuki Y.J., Tsuchiya M., Packer L

Yagi, H

GSH is found in all mammalian tissues as the most abundant non-protein thiol that defends against oxidative stress and possess a distinctive stability provided by a -carboxyl bond within the molecule (Figure 1A)
