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Its antibody is also used to reduce the severity of ARDS

[DOI] [PMC free article] [PubMed] [Google Scholar] 143.Filippi-Chiela E.C., Thome M.P., Bueno E., Silva M.M., Pelegrini A.L., Ledur P.F., Garicochea B., Zamin L.L., Lenz G

In H2O2-induced human corneal epithelial cells, esculetin (20-100 M) activates the Nrf2 signaling pathway, inducing the expression of multiple antioxidant genes, including HO-1, quinone 1 (NQO1), glutamate cysteine ligase modifier subunit (GCLM), SOD1 and SOD2, thereby inhibiting ROS generation and accumulation (37)

10.3389/fmicb.2024.1390722 Front Microbiol

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