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Insert the needle at 45 Use an insulin syringe (29-31 gauge)

The injection site reactions are more prominent than GLP-1s but not treatment-limiting for most people

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Notably, approaches that aim to reprogram TAMs towards an anti-tumor phenotype, such as by promoting macrophage polarization towards an M1-like phenotype or enhancing macrophage-mediated antigen presentation and T cell activation, hold great potential for cancer immunotherapy