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Subcutaneous injection protocols Injectable GHK-Cu delivers the peptide directly into tissue, bypassing the absorption limitations of topical application

From our point of view, therapeutic options must not only be directed to reach a molecular target, which ultimately would represent a fixed picture of the disease, but also to restore physiological global context in terms of nitro-oxidative stress and inflammatory response, just as the antioxidant treatment seems to act

Although PDE5I may have positive effects on improving NO and endothelial NOS and inhibiting ROCK [179], but more clinical evidence is still needed to support it

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