glutathione is a tripeptide containing a centralresidue Structure of the (GSH). Glutamic acid (Glu) Glutathione-driven redox decisions in cell
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The effect of desferrithiocin, an oral iron chelator, on T-cell function
Secondly, since cardiomyocytes are easily affected by free iron overload, the release of excess free iron during ferroptosis would result in up-regulation of transferrin receptor (TFR) and down-regulation of ferritin, promoting cardiomyocyte cell death through mitochondrial VDAC2/3 or membrane lipid peroxidation through Fenton reaction to induce myocardial edema and dysfunction (Liu et al., 2018)

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