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[DOI] [PMC free article] [PubMed] [Google Scholar] 149.Liew Z, Ritz B, Virk J, et al

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It is synthesized intracellularly as a 31 kDa precursor form, pro-IL-1, which is cleaved by Caspase-1, activated by inflammasomes (such as NLRP3, NLRC4, AIM2, etc.) into a 17 kDa mature form, and is subsequently released from the cell through non-conventional secretion [342]

Instead, the NmlR regulon in this bacterium has been linked to the response to general thiol/disulfide stress
