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The effect of L-carnitine in the expression of matrix metalloproteinases by human dermal fibroblasts

The Mitochondrial Unfolded Protein Response (UPRmt) Is Upregulated in Acute Myeloid Leukemia (AML) and Inhibiting the UPRmt Protease, LONP1, Leads to Mitochondrial Protein Aggregation and Cell Death Selectively in AML

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Specifically, the mitochondrial enzyme SHMT2 is significantly downregulated in HD animal models, leading to the accumulation of homocysteine [102]