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According to this paradigm, higher loop gain is associated with greater probability of breathing instability as chemoreflex responses to changes in PaCO 2 are likely to be disproportionate and result in ventilatory overshoots that reduce PaCO 2 below the apneic threshold

[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Zhou X., Speer R.M., Volk L., Hudson L.G., Liu K.J

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Tamborlane WV, Barrientos-Prez M, Fainberg U, Frimer-Larsen H, Hafez M, Hale PM, et al