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Endoplasmic reticulum The endoplasmic reticulum is another important source of ROS, mainly hydrogen peroxide, a subproduct of the process of protein folding (Li et al

We explained that this non-monotone behavior of the female GSH curve is caused by the inhibition of GCL and GS by GSH

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, Dysregulation of the glutamate cycle leading to glutamate hyperactivity and excitotoxicity has been implicated in the pathogenesis of neurodegenerative disorders such as PD

One important factor is homocysteine