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Magliozzi R, Howell OW, Reeves C, Roncaroli F, Nicholas R, Serafini B, Aloisi F, Reynolds R
In an effort to develop a non-invasive imaging method for assessing glutamine metabolism, we previously reported that magnetic resonance imaging (MRI) can be used to measure the initial uptake of glutamine in cancers 8

In our study, metformin acted via APMK-dependent mechanism and we found that it increased partial and total AMPK1 in AMN and cALD patient-derived cells consistent with a previous report [98] suggesting metformin can be a potential therapeutic agent for X-ALD

Therefore, when a patient with ulcerative proctitis develops a relapse of his or her disease, the inflammation usually is confined to the rectum
