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10.1002/anie.202300379
In order to identify drivers of lapatinib tolerance, we focused on clusters 2 and 9 which comprised transcripts exhibiting sustained increased expression throughout the time course of the experiment
After cooling, the glass coverslips were broken off, and the samples were cut using an ultramicrotome (EM UC6, Leica Microsystems, Wetzlar, Germany) into thin sections of ~200 nm, and then placed on Silicon wafers (Siegert Wafer GmbH, Aachen, Germany)
A., Lee, W., Giblin, F
In other mammals, such as rodents, it has been reported that the SNc of aged rats shows an important decrease in TH protein content, accompanied by a significant reduction in dopamine levels
