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10.1073/pnas.1202774109 16 ChaiR.XiaA.WangT.JanT
513 Vedolizumab, a monoclonal antibody, is used primarily for the treatment of moderate-to-severe UC by targeting 47 integrins, blocking the homing pathway of colonic lymphocytes, and reducing the inflammatory response in the intestinal tract

doi: 10.1007/s11947-022-02801-8 165 LiWZhangXHeZChenYLiZMengTet al

Similarly, B is the effect of the genetic component of the second exposure on the outcome trait, after accounting for the genetic component of the first exposure and for the two exposures genetically regulated co-expression
