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As used herein, "conditions which allow alkylation of the sulfhydryl group of GSH with the maleimide" typically require that the maleimide (such as NEM) is (initially) present at a concentration of at least 0.0001 mM, preferably at least 0.001 mM, more preferably at least 0.01 mM, even more preferably at least 0.1 mM, yet even more preferably at least 1 mM or even at least 2 mM

Dhonukshe-Rutten, R

This hypothesis was tested in several studies exploring the potential of combined therapies of PDEi with classical cytotoxic agents

Grce son rle cl dans la protection des cellules et le maintien de lquilibre interne, il constitue un alli intressant pour ceux qui souhaitent soutenir leur vitalit et leur bien-tre gnral

doi: 10.1016/j.freeradbiomed.2014.09.032