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This may function as a form of shutoff by preventing the activation of pro-inflammatory pathways such as NF-B and interferon responses, which are typically triggered by oxidative stress

1993;101:143S7

[DOI] [PMC free article] [PubMed] [Google Scholar] 98.Hoot KE, Oka M, Han G, Bottinger E, Zhang Q, Wang XJ

A regioselective synthesis of E-guggulsterone
Ginger repairs intestinal tissue by increasing goblet cell numbers, aiding defense through mucin production, and reducing inflammatory cell infiltration by lowering pro-inflammatory cytokines such as IL-1, TNF- , and IL-6 (93)
