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Researchers used LPS to establish a severe pneumonia mouse model, and genomic analysis confirmed that pulmonary endogenous bacteria can translocate to the brain and drive the transition of microglia and astrocytes from a resting state to an activated state via infection-associated pathways, thereby disrupting brain homeostasis [262]

The viscosity of the synovial fluid decreases due to the depolymerization of hyaluronic acid in the absence of hyaluronidase enzyme and no depletion in hyaluronic acid by synovial fluid proteases

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A family of Ca 2+ pumps comprising four members that pump Ca 2+ from the cytosol to the extracellular milieu

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