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Patient Convenience : Once-daily dosing, no injections

Specically, path A is inactive because the energy barrier associated with direct dissociation of the methyl ligand is higher than the barrier of intersection between two dierent electronic states: a metal-to-ligand charge transfer state (MLCT), and a ligand eld state (LF) along the CoO coordinate of the S 1 PES

Reducing the likelihood of severe illnesses

As injections are more easily and quickly absorbed by the body, many people use B12 injections as opposed to oral supplements

It is worth noting that fatigue may appear before anaemia develops in some cases, as the neurological and metabolic effects of B12 deficiency can manifest independently of haematological changes