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(2020) 580:E10

For the last 2 months, the patient had been consuming THP and tramadol for recreational purposes, without any medical indications

Furthermore, the balance between the reduced (GSH) and oxidized (GSSG) forms of glutathione is regulated by various intracellular enzymes, such as glutathione reductase, whose activity directly affects GSH availability (109)

Nach der Aktivierung des IGF-1-Rezeptors werden zwei Hauptsignalwege ausgelst: PI3K/Akt, der die Proteinsynthese antreibt und den Abbau hemmt, sowie MAPK/ERK, der die Zellproliferation stimuliert

DOI: 10.1038/nm1004-1022 Wang, Y.X., Zhang, C.L., Yu, R.T., Cho, H.K., Nelson, M.C., Bayuga-Ocampo, C.R., Ham, J., Kang, H., Evans, R.M