glutathione gsh deficiency alters the vitamin D-metabolizing enzymes CYP27B1 and CYP24A1 in human renal proximal tubule epithelial cells and kidney of HFD-fed mice Glutathione deficiency induces epigenetic alterations
Description
Because of the many critical roles TGF- family members play in normal development and tissue homeostasis, potent inhibition of all TGF- signaling would likely lead to unacceptable toxicity

and Zhang, K.Z., 2017

PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndrome

PMID: 52 XuS.WeerachayaphornJ.CaiS

doi: 10.3389/fimmu.2018.00365