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At 3 h after full recovery, mice were subjected to the IGTT as described above, and an additional round of CSF sampling was performed immediately after the IGTT
Although the study was designed and powered to determine safety and tolerability, when we analysed volunteers in cohort 3 (200 mg/12 h) we found that volunteers with overweight or obesity showed a significant decrease in body weight in 15 days of treatment (Fig
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In our studies, all 25 (100%) meningiomas demonstrated a dominant concentration of the glutamine/glutamate complex
