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Jagadish S, Singer W, Kotagal S

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17 The activity of CPT I is inhibited by malonyl-CoA, 18, 19 which is generated by carboxylation of cytosolic acetyl-CoA, by the enzyme acetyl-CoA carboxylase (ACC)

453 CliffJMKingECLeeJSSeplvedaNWolfASKingdonCet al

640 In the DPN study, tanezumab provided effective pain reduction in DPN, with no safety concerns observed