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Hypoxia Inducible Factor 1 (HIF-1), a crucial transcriptional regulator of hypoxic responses, is upregulated under oxidative stress, which subsequently triggers a hypoxic response, enhances the transcription of angiogenic factors, such as vascular endothelial growth factor (VEGF), and mediates autophagy, mitophagy, and aerobic glycolysis [134]

Results have not been independently verified

Whilst the lethal oral dose is of the order of 1 to 3 grams, American studies indicate that a dose of 2 mg per kg bodyweight could result in harmful effects, this amounting to only 140 mg a day for a 70 kg adult male

Innate immunity Particles larger than 10 m generally get caught in the nose and throat and never enter the lungs 54,55

& Renfree, M