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Clin Nephrol 95(5):273277 Funding No funding was secured for this study

While vitamin B12 injections are commonly recommended for individuals with a diagnosed deficiency or those at risk of deficiency due to certain medical conditions or dietary restrictions, they can also benefit: Vegetarians and Vegans : Plant-based diets may lack sufficient sources of vitamin B12, making injections a valuable option for keeping optimal levels

On-Label vs Off-Label and Compounded Products Vitamin B12 injections are an established medical treatment for confirmed B12 deficiency and related conditions (for example, pernicious anemia and certain malabsorption states), as summarized by the NIH Office of Dietary Supplements in its Vitamin B12 fact sheet for health professionals

[DOI] [PMC free article] [PubMed] [Google Scholar] Kannt A

NICE notes that pernicious anaemia is the most common cause of Vitamin B12 deficiency in those aged 40-70, with an average onset age of 60 in white people and 50 in black people, although it can affect black women at a younger age