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Among these myelin-specific proteins, we can highlight the so-called inhibitory proteins: myelin associated glycoprotein (MAG), oligodendrocyte myelin glycoprotein (OMGp) and Nogo-A

Matthews JS, Adams JB

There are three known genes which encode this enzymatic activity in humans, ALDH1A1 , ALDH2 , and the more recently discovered ALDH1B1 (previously known as ALDH5 )

Several drugs are carried by system L into the brain, and there is a strategy to design drugs that resemble the amino acids L-histidine and L-tryptophan for enhanced CNS delivery through LAT1 transporter (Hall et al., 2019)

Decreased IL-10 receptors on astrocytes as a consequence of senescence lead to dysregulation of microglial activation, showing an exacerbated response (Norden et al., 2014, 2016)