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Recent studies have revealed that neuronal metabolic reprogramming, characterized by PDK4-mediated inhibition of pyruvate dehydrogenase and altered expression of PKM2/PKM1 isoforms, contributes to early-stage Alzheimers and Parkinsons diseases

Ferroptosis Ferroptosis is a form of iron-dependent non-apoptotic cell death characterised by the intracellular accumulation of iron ions, elevated levels of ROS and downregulation of GPX4 expression [123]

Fluorometric assay for screening anti-oxidative activity of vegetables

Garlic appears to have antihyperlipidemic effects by inhibiting intestinal microsomal TG transfer protein (MTP) expression (137) and blocking 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMGR) activity (138), which is necessary for lipid production

doi:10.1016/S1470-2045(13)70026-3
