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Description
Leptin recruits Creb-regulated transcriptional coactivator 1 to improve hyperglycemia in insulin-deficient diabetes
This is problematic because vitamin B12 deficiency can cause permanent neurological effects
It was proven that AMPK inhibited PUFAs synthesis by inhibiting acetyl-CoA carboxylase (ACC) activity
5K, S14C)
However, efforts must also focus on the interim strategy to slow neuron losses in brain structures impacted including neocortices, hippocampus, locus ceruleus and the nucleus basalis of Meynert by stimulating synaptogenesis, neurogenesis and reducing neuroinflammation and oxidative stress
