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Shrestha S, Freake HC, McGrane MM, Volek JS, Fernandez ML

Most patients can start LDN at a 1.125 mg dose which is 14 of the standard 4.5 mg dose and slowly work up by adding 14 tablet each week

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Animal models of drug self-administration, known for their strong validity in depicting drug intake and abuse, are considered standard models for elucidating human addiction behaviors 37
