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Instead of being reabsorbed (as occurs in males who are not genetically susceptible to the disease), the hematoma leads to the recruitment of inflammatory cells and proinflammatory cytokines, which inevitably results in the formation of chronic inflammatory tissue that evolves towards fibrosis [20,21]

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The study revealed that early intervention with bevacizumab on VEGF function improved BBB integrity, cerebrovascular response, and long-term memory in mice (Zhang and Zhang 2024)