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All participants reported the absence of neurological or psychiatric disorders and were evaluated with the MoCA battery to determine cognitive integrity and to exclude participants with MCI (YA: mean SD score = 27.4 3.86, range = 2430

These benefits extend far beyond simple moisturization, offering measurable changes in skin structure and function that contribute to a more youthful appearance

It may also cause weakness in the muscular structures of the pharynx, increasing the tendency for airway collapse, causing snoring and obstructive apnea

Although it may be doubtful if glutamate oxidation is necessary metabolically, it may be functionally very important for complete disposal of glutamate in the brain in vivo , with continuous glutamate de novo synthesis and degradation and paucity/absence of other disposal or dilution routes

Optimistically, its benefits may preclude the need for surgical intervention altogether
