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Single-cell transcriptomic profiling of CTCs collected during resting phases reveals elevated mitotic activity, providing a mechanistic basis for time-dependent metastatic potential and underscoring the importance of chronobiology in cancer diagnosis and therapy (176)

As a result, machine learning classification models have identified several circRNAs as potential disease biomarkers, such as circERBB2 and circCHST12 for intracerebral hemorrhage diagnosis (Bai et al., 2022), circ-0080695 for liver cancer diagnosis (Zhu et al., 2021b), circ_0059706 for acute myeloid leukemia prognosis (Ma et al., 2022b), and hsa_circ_0007919, hsa_circ_0002419, and hsa_circ_0005521 for pulmonary tuberculosis diagnosis (Yuan et al., 2022)

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[DOI] [PubMed] [Google Scholar] 104.Lauterburg B, Velez M