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Liver and spleen weights were expressed as a percent of the total body weight (for normal rats, liver 3.24.0% and spleen 0.200.26%)

Ishida, J., et al

PKM2 plays a central role in coupling glycolytic flux with inflammatory responses [25]

When administered properly under medical supervision, serious adverse effects are rare

Although folic acid absorption by the intestine is catalyzed by the proton-coupled folate transporter (PCFT), which has similar affinity for both folic acid and reduced folates ( Table 2 ) (65, 66), the affinity for folic acid of the reduced folate carrier (RFC), which is ubiquitously expressed in all tissues, is 50- to 150-fold lower than that for 5-methylTHF and other reduced folates (Table 2) (65, 66)