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We noticed that erastin-resistant cells exhibited higher basal level of NRF2 than that of parental cells (Fig

The results demonstrate that the combination therapy (ALA/PGE1) is significantly superior to either monotherapy ( p 60 ms occurred significantly more often in the placebo group than in the ALA group (5.0% vs

The mTOR pathway plays a key role in cancer activity and has also been shown to prevent iron-mediated cell death by regulating ROS production 20

First- and second-degree relatives of celiac patients have a 10- to 15-fold and a 2.5-fold increased risk, respectively, compared to the general population (Bai 2013