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Description
Combined targeting of AR signaling and glutamine metabolic pathways holds promise as a new strategy to improve CRPC treatment

Lactate buildup at the site of chronic inflammation promotes disease by inducing CD4 + T cell metabolic rewiring
244 Using large-scale in vivo CRISPR screening technology, researchers have identified the E3 ligase Cop1 within breast cancer cells as an essential regulator of macrophage chemokine secretion

doi: 10.1128/MCB.14.6.3604

Gleichzeitig steigt die Belastung durch oxidativen Stress hufig schneller an, als der Krper diesen kompensieren kann
