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Amino acid and protein modification by oxygen and nitrogen species

Moreover, adeno-associated virus (AAV)-mediated PHGDH inactivation in the brain decreased tissue l-serine and glycine levels and impaired synaptic plasticity and spatial memory (60), demonstrating that reduced l-serine levels in the brain contribute to cognitive dysfunction

PMID: 30273089

Journal Format Article) using a format determined by the Journal for Journal publication

However, this procedure is somewhat more onerous for the HPLC method because, after GSH is fixed in a complex, GSSG must subsequently be reduced to GSH prior to incubation with MBB