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While researchers note that the LD50 (lethal dose) for GHK-Cu in murine models equates to an impossibly massive single dose of roughly 23,000mg for a 70kg human adultrendering acute lethal toxicity highly improbable at the standard aesthetic therapeutic doses of 5-50mgthe long-term cumulative effects of daily copper peptide injections remain entirely unmapped in human populations

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(4) This interaction may be crucial as FOXO4, when bound to p53, may inhibit some of p53's key functions involved in cell cycle regulation and apoptosis

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Measuring the side effects of psychotropics: the behavioural toxicity of antidepressants