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In the SNI model, amitriptyline induced NF-KB (nuclear transcription factor-kappa B)-dependent upregulation of EAAT2 [403], reversed the downregulation of EAAT1 and EAAT2 and attenuated mechanical allodynia [304]

PPARd belongs to nuclear receptor superfamily of ligand-activated transcription factors

Introduction Epilepsy is a common disorder of the central nervous system (CNS), characterized not only by recurrent epileptic discharges but also by frequent and severe neuropsychiatric comorbidities, with depression being the most prevalent (Alhashimi et al., 2022)

Apoptosis 17 (11), 11561169 (2012)

Cortex 16, 12891295