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Elevated NAD+ levels activate sirtuins, particularly SIRT1, which are NAD+-dependent deacetylases that regulate numerous metabolic processes including fat oxidation, glucose metabolism, mitochondrial biogenesis, and cellular stress responses

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10.1080/08923973.2016.1274997 40 RaineT.BonovasS.BurischJ.KucharzikT.AdaminaM.AnneseV.et al (2022)
