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The pain can range from tingling and numbness to sharp, stabbing sensations and may exhibit temperature variations such as burning or cold

Dame Sheila Patricia Violet Sherlock

Introduction Parkinsons disease (PD) is a progressive neurodegenerative disorder characterized by motor symptoms resulting from -synuclein (-Syn) deposition and the loss of dopaminergic neurons (DA), which also contribute to non-motor and cognitive impairments ( Furthermore, approximately 10% of proteins in the human body undergo palmitoylation and are involved in numerous intracellular physiological functions ( Palmitic acid Palmitic acid (16:0

However, despite its promising therapeutic effects, the use of HGF protein is limited by its poor bioavailability

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