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Prior study showed that deficiency of Sentrin/SUMO-specific protease 2 (SENP2) resulted in hyper-SUMOylation of multiple potassium channels and neuronal hyperexcitability, finally triggering spontaneous seizures and sudden death [78, 79], which suggests that sumoylation is vital for epilepsy

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Psychosocial sensitization introduces two new terms: cognitive-emotional sensitization, explaining how selective attention to specific bodily pain can exacerbate the pain itself, and interpersonal sensitization, related to shared neuronal representation regarding the subjects pain experience [12]

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Parallel evolution in Pseudomonas aeruginosa over 39,000 generations in vivo