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In a prospective case-control study of 14,916 male physicians, those in the highest 5% of homocysteine levels had a 3.1x greater risk of heart attack compared with those in the bottom 90%

Nevertheless, despite demonstrating potent in vivo effects, neither study performed side-by-side dose-response benchmarking against clinical ACE inhibitors (e.g., lisinopril or captopril) under identical assay conditions

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Mean GSH levels increased consistently with time relative to baseline (Table 2 and Figure 3a,b), although levels fluctuated somewhat among individual subjects (Figure 3c,d)

Although dietary Met is as effective as dietary Cys in the upregulation of CDO, the effectiveness of Met depends upon a functioning transsulfuration pathway (Cresenzi et al