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Roles of cytokines and chemokines TNF- TNF- is a pro-inflammatory cytokine primarily produced by macrophages and monocytes, playing a critical role in inflammatory and immune responses [123]

doi: 10.1212/01.WNL.0000166038.67153.9F 105

Moran Journal of Personalized Medicine.2026

10.1056/NEJM198903023200904 N Engl J Med

This has been observed particularly in individuals with HIV, resulting in the classic wasting syndrome that accompanies HIV infection (Shikuma)
