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British Journal of Anaesthesia 1999;82(2):2779

However, the presence of parietal cell antibodies is nonspecific and occurs in other autoimmune states

The RCTs showing IGF-I elevation have not consistently demonstrated statistically significant changes in DXA-measured lean mass in non-GH-deficient populations

It was first characterized as an incretin hormone, meaning it enhances glucose-stimulated insulin secretion from the pancreatic beta cells

However, such a wide range of even opposite disturbances that can be all attenuated/counteracted, given a general counteracting potential, can match with the original cytoprotection concept perception holding the equal cell protection (necrosis prevention) against a variety of different agents (originally used absolute alcohol, boiling water, strong base, and strong acid claimed for common endogenous mechanisms)