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Steinberg, Department of Pharmacology, College of Physicians and Surgeons, Columbia University, 630 West 168 Street, New York, NY 10032, USA, [email protected] This article was submitted to Cardiovascular and Smooth Muscle Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Because fat-7 expression is significantly compromised by nhr-49 deletion, and because lowered fat-7 expression can lead to shortened life span, we suggest that the reduced life-span phenotype of nhr-49(nr2041) likely reflects, at least in part, diminished fat-7 expression

and his LDL-P increased from 1,143 to 2,259 (Figure 1A)

elegans is a meaningful model to study the interaction among microbiota, pathogen, and food: the worms use bacteria as food, and the laboratory culture is a mono-association