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It has been shown to reverse pathological expression of 70% of genes in a gene signature for metastasis-prone colon cancer and to shift gene expression in COPD lungs from destruction to healthy remodeling

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The primary mechanism of NO mediated wound healing is the formation of new blood vessels in a process called angiogenic repair

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The advisory committee's recommendation is not binding, but historically the FDA adopts PCAC vote outcomes in its final 503A bulk substance determinations