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This is one of the first peptide-based therapies for disc disease to reach human clinical trials, and its outcomes will significantly influence the field

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Other signal pathways, such as the Wnt/-catenin and Notch pathways, are also involved in fibroblast activation and transformation (250, 251)

Prevention isn't just possible, it's essential

It is not metabolized and not involved in gluconeogenesis, thereby not constituting a direct energy source (5)
